Case study on Biochemistry Essay Example | Topics and Well Written Essays - 1000 words

Case study on Biochemistry - Essay Example When the cycle is incomplete, and the product is not formed, the function of the organism cannot properly take place. Without enzymes, the reactions needed for biological processes of the body would take at a slower rate or fail to take place. This is detrimental to the well-being of the organism involved. One of the most important enzymatic actions is the breakdown of fructose. This is a simple sugar found in some of foods such as fruit and honey. This is essential as it plays an immense role in supply of energy for the body. However, fructose is not a direct source of energy, but enzymes are required to breakdown fructose into a reliable energy. After eating, catabolism of fructose takes place through fructolysis. The process begins with the enzyme fructokinase and produces fructose 1-phosphate as a product. The second step is enhanced by aldose. This enzyme breaks down fructose 1-phosphate into two products: dihydroxyacetone phosphate (DHAP) and glyceraldehydes. The products enter the process of glycolysis to ensure the body gets its energy requirement and extra glucose. The absence of enzymes necessary for the breakdown of fructose leads to poor response of the body with repeated ingestion of foods containing fructose (NLM, 2011). Explain how a deficiency in aldolase B can be responsible for hereditary fructose intolerance. Aldolase B plays a significant role in the breakdown of fructose. The absence of the enzyme leads to accumulation of fructose-1-phosphate in the liver cells (NLM, 2011). The accumulation of this substance is toxic, and overtime leads to the death of liver cells (Breakspear Medical Group Ltd, n.d.). Additionally, fructose-1-phosphate fails to release the phosphate group required for repeated ATP production and control of stored sugar (NLM, 2011). Several defects arise due to death of liver cells and low number of phosphate groups. They include hypoglycemia, liver abnormalities, and other forms of hereditary fructose intolerance (NLM, 2011 ). Provide clearly labeled diagrams to demonstrate: Diagram lock and key models of enzymatic activity. Diagram showing how enzymes function as a lock and key. Diagram the effect of enzymes on activation energy. Discuss the specific substrate acted on by aldolase B. Enzymes are usually specific in nature. They only act to a unique substrate. Aldolase B also demonstrates this uniqueness. Fructose-1-phosphate (F1P) is acted upon by aldolase B. This is the only enzyme that binds on F1P as its substrate. The breakdown leads to the formation of two products that are further metabolized to produce glucose, lactate and uric acid (NLM, 2011). Explain the role of aldolase B in the breakdown of fructose. Aldose B plays an essential role in the breakdown of fructose. The enzyme breaks down fructose-1-phosphate into dihydrooxyacetone phosphate (DHAP) and glyceraldehydes (NLM, 2011). The two products enter the process of glycolisis to answer to body requirements for energy, or increased level of glucose. B. Case two Explain what would happen to the amount of energy available to a cell if the entire Cori cycle occurred and remained within that single cell (i.e., a muscle cell). In the skeletal muscles, there are few mitochondria, and yet they consume a lot of energy. This leads to depletion of oxygen and the muscles are forced to operate without oxygen. The Cori cycle is essential as it links this process with gluconeogenesis in the liver. This means that the lactate produced by the muscle cells travels through the blood into the liver

Proof read Essay Example | Topics and Well Written Essays - 2250 words

Proof read - Essay Example 3 Opportunity This report was designed to enhance the understanding of the benefits of donating recycled electronics or â€Å"e-waste† through Free Geek. It seeks to answer the following questions: Why is it necessary to recycle e-waste? What is Free Geek and how does it promote environmental sustainability and education? How can Intel’s donations to Free Geek benefit the e-waste problem locally and globally? What benefits can Intel expect if they donate to Free Geek? Background Over the last couple of decades, Intel has been a leader in technology, advancing not only technology, but the way the world interacts with it. Intel is at the forefront of the computer chip manufacturing industry and is possibly the most influential technology companies in the past century. Intel’s leadership and influence has set standards for similar companies for the betterment of the environment. Free Geek, a local non-profit organization in Portland Oregon, describes itself in the c ompany’s mission statement as an organization that firmly believes that recycling is best done through â€Å"reuse†. Owing to this philosophy, the company refurbishes whatever it can and gives it back to the community â€Å"with a new lease on life†. This way the stuff doesn’t get thrown into the garbage or used for landfills to filter toxins from the soil nor is it dumped to developing countries to be disassembled by young ones. The company makes sure that all electronic materials that are not reused are recycled in a responsible manner within the confines of North America. Imagine the possibilities if two forward thinking companies worked together with a common goal for the greater good of all humanity.   This report shall shed light on the downfalls of e-waste, the benefits of cooperation, and the positives of donation.   While e-waste is a global calamity, this report shall focus on a smaller scale, primarily the United States.    Discussion of Findings Hazards and Effects of E-waste E-waste has many negative effects on the livelihood of humans, animals and their natural habitats. Polybrominated diphenyl ethers are a component of e-waste that is used as flame retardants in plastics in high tech electronics. This chemical compound is synthetic and is not a product of nature. It mainly includes bromine with some amounts of chlorine, fluorine, iodine and astatine. This compound works by releasing bromine atoms that depletes the surrounding oxygen in the air. PBDEs are toxic in that they are responsible for the disruption of thyroid hormones, deficits in neurodevelopment and cancer (Hooper and McDonald). These PBDEs have been detected in marine mammals everywhere from the Baltic Sea to the Great Lakes and are found in humans in the United States at higher levels than anywhere else in the world (Grossman 113). Since only 15-20% of e-waste is recycled in the U.S. it is questionable where the rest goes (U.S Environmental Protecti on Agency). â€Å"On the outskirts of Ghana’s biggest city sits a smoldering wasteland, a slum carved into the banks of the Korle Lagoon, one of the most polluted bodies of water on earth† (WGBH Educational Foundation). Exported e-waste has a huge impact in a lot of developing countries. These developing countries offer a very inexpensive recycling service although most workers work in extremely unsafe environments. Tests revealed the presence of purely acidic soil near some of the work areas having a pH level of 0 (Grossman 187). Impact of Corporate Recycling of